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Drug

Pharmaceutical

With quality service based on our experience and expertise, we are dedicated to assist your R&D and commercial manufacturing of API at any phase with services for lead generation & optimization, process chemistry, and GMP manufacturing of API.

Drug Discovery ----- making the most of our base technologies

A variety of technologies in hand, we are prepared to serve you to meet your needs in leading-edge drug discovery R&D, in particular, organic synthesis together with purification technology to produce complex molecules, and genetic engineering to produce chemicals and proteins such as enzyme, phase Ⅱ metabolite, antibody using microbial and mammlian cells.

Drug Discovery

Combinatorial Synthesizer
(LC-MS and centrifugal concentrator)

Development phase ----- services with organic chemistry and biochemistry

We have a lot of experience in services at development phase. In early development phase, the following are examples of our synthesis service. Drug candidate and derivatives, reference drug, metabolite, stable isotope labeled compound, metabolite, degradation compound, peptide, nucleotide, sugar, and chemical library. Request for synthetic method study is also welcome.

In advanced phase, we feature scale-up study and manufacture of API for clinical trial use. Column purification, sometimes inevitable at this phase, can be handled with 250 and 300-liter-column.
Not only chemical synthesis but also cultivation is ready for service. With up to 2,000-liter-fermentor and purification system, manufacture and scale-up study services are available.

Drug, Development phase

Program controlled low temperature reactor (-70 ℃)
(Employed for Ozonolysis)

Commercial Manufacture ----- c-GMP complied facillity at Izumo

Izumo Plant has plants dedicaed to manufature API and intermediates, installed with vessels up to 6,000 liters, centrifugal filter, conical dryer, jet mill, and more. We have carried out a variety of reactions for API manufacuring, and please rest assured on our experience. We are pleased to cooperate with you continuously from development phase to commercialization.
License for Drug Manufacturing Operation and License for Psychotropic Drug Manufacturing (Japan) have been gained.

manufacturing/analysis equipment
Izumo plant

Drug, Commercial Manufacture

1,000-liter-glasslined vessel at Izumo plant