Fluorination

Technology

Fluorine atom has been introduced to pharmaceuticals and agrochemicals to increase acivity and reduce toxicity. Manufacturing and/or R&D study of fluorinated compounds is welcome.

see some examples(PDF/137KB)

Experiences

Fluorination with DFI, BAST, DAST, Ishikawa's Reagent, NFSI, KF, HF-Pyridine.

Capability

Synthesis of fluorinated compound using flurinating agents, fluorinated building block, and in-situ genrated HF.
Teflon-coated 150-litter-vessel, with operating temperature from -70 to +70 Centigrade, is ready for service. Our service extends to consultation by our medicinal chemist on molecule design of fluorinated compounds in drug discovery.